Scientist - LC-MS Bioanalytical

Company: Amgen
Location: Thousand Oaks
Posted on: March 6, 2026

Job Description:

Join Amgens Mission of Serving Patients At Amgen, if you feel like youre part of something bigger, its because you are. Our shared missionto serve patients living with serious illnessesdrives all that we do. Since 1980, weve helped pioneer the world of biotech in our fight against the worlds toughest diseases. With our focus on four therapeutic areas Oncology, Inflammation, General Medicine, and Rare Disease we reach millions of patients each year. As a member of the Amgen team, youll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives. Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, youll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career. Scientist - LC-MS Bioanalytical What you will do Lets do this. Lets change the world. In this vital role, you will support the design, development, validation, and implementation of robust LC-MS/MS bioanalytical methods for a wide range of therapeutic modalitiesincluding small molecules, oligonucleotides, proteins, and other complex molecular entitiesto enable GLP preclinical and regulated clinical studies. Given the scope of projects, the role will involve multidisciplinary interactions with scientists across research and development at Amgen. The position is lab-based, and has significant emphasis on data management/fidelity, report generation, effective time management, communication, and data presentation. Perform quantitative bioanalytical experiments and organize data and results, including planning and running LC-MS/MS bioanalysis and preparing and analyzing biological samples Develop and implement LC-MS/MS bioanalytical methods with quick turnaround times. Conduct small and large molecule bioanalysis in non-clinical and clinical samples from various matrices (plasma, urine, CSF, tissues). Perform biological sample extraction using protein crash (PPT), SPE, LLE, and/or affinity capture methodologies. Generate complete, accurate, and concise documentation using electronic systems and laboratory notebook Ensure bioanalytical data meets regulatory expectations for global submissions by maintaining accurate records and staying current with industry guidelines. Author study reports, standard operating procedures, analytical methods, memos, and other regulatory-compliant documents. Communicate bioanalytical data to key discovery and development teams, contribute to scientific publications, and present at professional meetings. Comply with safety guidelines and site-specific procedures which include but is not limited to the completion of training on assigned tasks, maintenance of training records, laboratory documentation, and following detailed SOPs and other written procedures. Perform general laboratory housekeeping activities and operational support as needed, including QC of reports. What we expect of you We are all different, yet we all use our unique contributions to serve patients. The scientific professional we seek is a key contributor with these qualifications. Basic Qualifications: Doctorate degree Or Masters degree and 2 years of relevant industrial/technical experience Or Bachelors degree and 4 years of relevant industrial/technical experience Preferred Qualifications: Prior experience in CRO or pharma/biotech strongly desired Strong technical expertise in quantitative mass spectrometry on triple quadrupole (QQQ) platforms as well as HRMS Experience with an array of analytical technologies that can accelerate bioanalysis inclusive of automation and/or micro-sampling Prior GLP and GCP experience. Demonstrated expertise in working with a variety of sample types (e.g., blood, plasma, serum, tissues, cerebrospinal fluid) and employing diverse sample preparation techniques (e.g., SPE, LLE, immunocapture) to support analysis of different therapeutic modalities, including small and large molecules by LC-MS. Prior experience in bioanalytical (regulated) assay execution and transfer to CROs Must be willing to work in a fast-paced, multi-project environment with high workload demands, and consistently deliver high-quality results within established timelines. Demonstrated ability to resolve scientific challenges efficiently and prioritize effectively Excellent scientific problem-solving skills Excellent project and time management abilities Ability to work collaboratively with internal and external stakeholders Supervisory and mentoring experience in a lab-based setting What you can expect from us As we work to develop treatments that take care of others, we also work to care for your professional and personal growth and well-being. From our competitive benefits to our collaborative culture, well support your journey every step of the way. The expected annual salary range for this role in the U.S. (excluding Puerto Rico) is posted. Actual salary will vary based on several factors including but not limited to, relevant skills, experience, and qualifications. In addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include: A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan Stock-based long-term incentives Award-winning time-off plans Flexible work models where possible. Refer to the Work Location Type in the job posting to see if this applies. Apply now and make a lasting impact with the Amgen team. careers.amgen.com In any materials you submit, you may redact or remove age-identifying information such as age, date of birth, or dates of school attendance or graduation. You will not be penalized for redacting or removing this information. Sponsorship Sponsorship for this role is not guaranteed. As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients. Together, we compete in the fight against serious disease. Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or any other basis protected by applicable law. We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation. Amgen is an Equal Opportunity employer and will consider you without regard to your race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status.

Keywords: Amgen, Cerritos , Scientist - LC-MS Bioanalytical, Science, Research & Development , Thousand Oaks, California